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Mouse anti alpha Fodrin IgG IgA,A Fodrin IgG IgA ELISA Kit

Mouse anti alpha Fodrin IgG IgA,A Fodrin IgG IgA ELISA Kit

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(PDF) Clinical and immunological characteristics of type 1

4.Ruffatti A,Ostuni P,Grypiotis P et al.Sensitivity and specificity for Another important finding of our study was an increased primary Sjo¨grens syndrome of IgA and IgG anti-alpha-fodrin percentage of CD71 positive T-helper cells and HLA-DR positive antibodies detected by ELISA.(PDF) Sjögrens SyndromeStudy of Autoantigens and Academia.edu is a platform for academics to share research papers.

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Antibody isotype ELISA kit Cat # Species Total Igs# IgG -Specific IgM SpecificIgA Other Isotypes Autoimmune ELISA Kits (Mouse,Rat,Human etc) Alpha Diagnostic Intl Inc.,(800) 786-5777 Mouse 5010 Anti-Fodrin Human 3300-160-AFG Thrombosis-Diagnostics3164 -Fodrin-Check - AESKU.GROUP - Experts in DiagnosticsIntended Use AESKULISA -Fodrin-Check is a solid phase enzyme immunoassay for the combined quantitative and qualitative detection of IgA and IgG antibodies against -Fodrin..Recombinant Antigens Alpha-Fodrin.Native Antigens n.a.

3164 -Fodrin-Check - AESKU.GROUP - Experts in Diagnostics

Intended Use AESKULISA -Fodrin-Check is a solid phase enzyme immunoassay for the combined quantitative and qualitative detection of IgA and IgG antibodies against -Fodrin..Recombinant Antigens Alpha-Fodrin.Native Antigens n.a.ALPCO Product Directory Equipment Reviews onHelp over 2 million scientists like you save time,money resources; Be the first to review brand new products; Exclusive perks,regular competitions,prizes and member-only events; Give vital feedback to manufacturers help shape new technologies

ASCA IgG/IgA ELISA-Test-Kit,zur Differential-Diagnostik

Anti-alpha-Fodrin IgG/IgA; Anti-C1q; Anti-CCP hs ASCA IgA.ASCA IgA ist ein auf der ELISA Technik basierendes,automatisiertes In-vitro-Testsystem für die quantitative Bestimmung von IgA-anti-Saccharomyces cerevisiae-Antikörpern (ASCA) in humanem Serum oder Plasma,die gegen Mannan in der Zellmembran von S.cerevisiae gerichtet sind.Acids Bases - MP BiomedicalsUnless specified otherwise,MP Biomedical's products are for laboratory research use only,not for human or clinical use.For more information,please contact our customer service department.

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Unless specified otherwise,MP Biomedical's products are for laboratory research use only,not for human or clinical use.For more information,please contact our customer service department.Alfa fodrina y diagnóstico de síndrome de Sjögren primario ·Translate this pageJan 01,2019·This is caused by lymphocytic infiltrates and neuroendocrine components.The diagnostic criteria in this syndrome have subjective and non-specific elements,but in the last few years the performing of IgA and IgG anti-alpha-fodrin antibodies has been considered as a diagnostic option.

Alpha Fodrin Ab IgG/IgA ELISA Kit - Abnova

Alpha Fodrin Ab IgG/IgA ELISA Kit is an enzyme immunoassay for quantitative determination of IgG and IgA class Anti-alpha-Fodrin Autoantibodies in human serum or plasma.Background Alpha-Fodrin is an intracellular,actin-binding,organ-specific protein of the cytoskeleton.It is a dimer composed of an alpha- and a beta-subunit.Alpha Fodrin ELISA Kit (Colorimetric) (KA1087) Novus Alpha Fodrin IgG/IgA ELISA Kit is an indirect solid phase ELISA for the quantitative measurement of IgG and IgA class autoantibodies against alpha-Fodrin in human serum or plasma.

Alpha fodrin and primary Sjögren's syndrome diagnosis

The article evaluates the diagnostic performance of the anti-alpha fodrin antibodies IgA and IgG in our population,using ELISA.As mentioned in the article,fodrin is a protein of 240 KD that is part of cytoskeleton and bound to actin.It is made up by heterodimmers of one and one subunit.In 1997,Haneji et al.,in an important Alpha-Fodrin Antibody IgG/IgA ELISA Kit (DEIA1874 Alpha-Fodrin Antibody IgG/IgA ELISA Kit is an indirect solid phase enzyme immunoassay (ELISA) for measurement of IgG and IgA class autoantibodies against alpha-Fodrin in human serum or plasma.

Alpha-fodrin as a putative autoantigen in Graves

The anti--fodrin ELISA was produced by incubating microtitre plates (Costar,Germany) with target protein (05 µg/ml) diluted in phosphate-buffered saline (PBS) (100 µl per well) overnight at 4°C according to.Flicking and slapping removed the antigen solution.Alphafodrin as a putative autoantigen in Graves Apr 01,2005·Using sera from patients with SS,the antigenicity of the purified fodrin fragment was demonstrated by immunoblotting.Sera from 144 patients with GO and 1200 blood donors were screened for the presence of antifodrin IgA and IgG antibodies by a newly developed ELISA using the human fodrin fragment as an autoantigen.

Alphafodrin as a putative autoantigen in Graves

Apr 01,2005·Using sera from patients with SS,the antigenicity of the purified fodrin fragment was demonstrated by immunoblotting.Sera from 144 patients with GO and 1200 blood donors were screened for the presence of antifodrin IgA and IgG antibodies by a newly developed ELISA using the human fodrin fragment as an autoantigen.Anti--fodrin autoantibodies are not useful diagnostic The presence of anti--fodrin (IgG and IgA) antibodies in the serum was investigated using a commercial enzyme linked immunosorbent assay (ELISA) technique (Aesku Lab Diagnostika,Wendelsheim,Germany),which employs recombinant 93 kDa -fodrin as the antigen,and a home produced ELISA using as the antigen a synthetic -fodrin peptide corresponding to the 20 amino terminal residues of human -fodrin

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Anti-B.pertussis Toxin.Bordetella pertussis,der Erreger des Keuchhustens,ist ein kleines,gramnegatives Bakterium aus der Gruppe der Kokkobazillen.Es wird durch Tröpfcheninfektion übertragen und ist hoch ansteckend.Keuchhusten gehört zu den gefährlichsten Infektionskrankheiten für Säuglinge die Krankheit kann bei ihnen tödlich enden.Anti-Cardiolipin IgG/IgM ACR Klassifikations-Kriterium Alle Anti-Cardiolipin-Tests von ORGENTEC sind mit humanem beta-2-Glycoprotein I als Kofaktor beschichtet.Anti-Cardiolipin IgG/IgM.Anti-Cardiolipin IgG/IgM ist ein ELISA-Test zur quantitativen Bestimmung von IgG und IgM- Antikörpern gegen Cardiolipin in humanem Serum oder

Anti-Cardiolipin IgG/IgM ACR Klassifikations-Kriterium

Alle Anti-Cardiolipin-Tests von ORGENTEC sind mit humanem beta-2-Glycoprotein I als Kofaktor beschichtet.Anti-Cardiolipin IgG/IgM.Anti-Cardiolipin IgG/IgM ist ein ELISA-Test zur quantitativen Bestimmung von IgG und IgM- Antikörpern gegen Cardiolipin in humanem Serum oderAnti-Phospholipid Screen IgG/IgM ELISA-Test-Kit Anti-Phospholipid Screen IgG/IgM.Anti-Phospholipid Screen IgG/IgM ist ein ELISA-Screeningtest für die quantitative Bestimmung von IgG und IgM-Antikörpern gegen Cardiolipin,Phosphatidyl Serin,Phosphatidyl Inositol,Phosphatidsäure und den Kofaktor beta

Anti-alpha-fodrin antibodies in patients with Sjögrens

Anti-alpha-fodrin antibodies in patients with Sjögrens syndrome secondary to rheumatoid arthritis taBLE 2 Association studies of demographic,clinical and serological data with IgA and IgG anti-AF antibodies in 90 RA patients Variables Anti-AF IgA Anti-AF IgG Positive n = 46 Negative n = 44 p Positive n = 21 Negative n = 69 pAnti-alpha-fodrin antibodies in patients with Sjögrens Anti-alpha-fodrin antibodies in patients with Sjögrens syndrome secondary to rheumatoid arthritis taBLE 2 Association studies of demographic,clinical and serological data with IgA and IgG anti-AF antibodies in 90 RA patients Variables Anti-AF IgA Anti-AF IgG Positive n = 46 Negative n = 44 p Positive n = 21 Negative n = 69 p

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Antibodies against alpha-fodrin in Sjögren's syndrome

Mar 01,2003·Indeed,64% of the pSS patients had IgA antibodies against alpha-fodrin.So far,72% of all patients classified according to European criteria had IgA and/or IgG antibodies against alpha-fodrin.In more recent studies,we have additionally screened pSS patients classified according to the San Diego criteria .San Diego criteria differ from the Antibodies to alpha-fodrin derived peptide in Sjögren's Apr 01,2006·Sensitivity and specificity for primary Sjögren's syndrome of IgA and IgG anti-alpha-fodrin antibodies detected by ELISA.Ruffatti A,Ostuni P,Grypiotis P,Botsios C,Tonello M,Grava C,Favaro M,Todesco S.J Rheumatol,31(3):504-507,01 Mar 2004 Cited by 15 articles PMID 14994395

Antibodies to alpha-fodrin derived peptide in Sjögren's

Apr 01,2006·Sensitivity and specificity for primary Sjögren's syndrome of IgA and IgG anti-alpha-fodrin antibodies detected by ELISA.Ruffatti A,Ostuni P,Grypiotis P,Botsios C,Tonello M,Grava C,Favaro M,Todesco S.J Rheumatol,31(3):504-507,01 Mar 2004 Cited by 15 articles PMID 14994395Aromatase-deficient mice spontaneously develop a Aug 24,2004·Measurement of Anti--Fodrin and Anti-DNA Antibodies by ELISA.The serum level of anti--fodrin antibody was determined by ELISA; positive mouse serum and human recombinant -fodrin protein were provided by Y.Hayashi (Tokushima University School of Dentistry,Tokushima,Japan) .Serial dilutions (1:501:5,000) of test serum samples were used.

Aromatase-deficient mice spontaneously develop a

Aug 24,2004·Measurement of Anti--Fodrin and Anti-DNA Antibodies by ELISA.The serum level of anti--fodrin antibody was determined by ELISA; positive mouse serum and human recombinant -fodrin protein were provided by Y.Hayashi (Tokushima University School of Dentistry,Tokushima,Japan) .Serial dilutions (1:501:5,000) of test serum samples were used.Associations of Anti-Aquaporin 5 Autoantibodies with Nov 03,2019·Associations of Anti-Aquaporin 5 Autoantibodies with Serologic and Histopathological Features of Sjögren's Syndrome.1 Coronavirus Find the latest articles and preprints

Author Renato Nisihara,Thelma L.Skare,Elisa Cenci,Denise Gabardo,Flavia Nass,Shirley R.R.UtiyamaPublish Year 2016Small Interfering RNA Targeting -Fodrin Suppressing the

·Anti--fodrin IgG and IgA antibodies were critical to diagnosing pSS.The results of this study underscored the complexity of the immune regulation mechanism by -fodrin in the SS mice.Our ultimate goal was to understand the role of -fodrin in regulating the levels of inflammatory factors in pathogeny of SS mice.Autoantibodies to alfa-fodrin in patients with Hashimoto Apr 23,2008·Correlation was found between the level of IgG alfa-fodrin and anti-thyroglobulin antibodies.Based on these findings,fodrin can be associated with both endocrine and exocrine glandular secretion.Antibodies to alfa-fodrin might have a role in the pathogenesis of Hashimoto thyroiditis concerning the final common effectory pathway,secretion.

Autoantibodies to alfa-fodrin in patients with Hashimoto

Apr 23,2008·IgA and IgG isotypes of aAF were detected by commercially available ELISA kits (Aesku.Lab Diagnostika,Wendelsheim,Germany),so were anti-Ro/SSA and anti-La/SSB antibodies (Hycor,Penicuik,UK),according to the manufacturers instructions.Autoantibody ELISA Kits Autoimmune ELISA KitsAntibody isotype ELISA kit Cat # Species Total Igs# IgG -Specific IgM SpecificIgA Other Isotypes Autoimmune ELISA Kits (Mouse,Rat,Human etc) Alpha Diagnostic Intl Inc.,(800) 786-5777 Mouse 5010 Anti-Fodrin Human 3300-160-AFG Thrombosis-Diagnostics

Autoantigen Array Houston Omics Collaborative

The samples will be treated with DNAse I,diluted 1:50,and incubated with the autoantigen array.The autoantibodies binding to the antigens on the array will be detected using Cy3 labeled anti-IgG and Cy5 labeled anti-IgM and the arrays will be scanned with GenePix&4300A Microarray Scanner.Buy Monkey ELISA Kits Monkey ELISA Kits Online+1-888.733.6849 +1-617.299.7367 (Intl) Our customer service representatives are available 24 hours,Monday through Friday to assist you.

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+1-888.733.6849 +1-617.299.7367 (Intl) Our customer service representatives are available 24 hours,Monday through Friday to assist you.Chicken Anti-alpha-Fodrin IgG/IgA ELISA Kit (ABIN1050478)This ELISA kit is a solid phase ELISA designed for quantitative determination of Anti-alpha-Fodrin IgG/IgA (A-Fodrin IgG/IgA).Sample Type Cell Culture Supernatant,Plasma,Serum,Tissue Homogenate Analytical Method Quantitative Components

Cited by 1Publish Year 2018Author Xiao-Lin Sun,Chun-Yan Pang,Yuan Liu,Wei Zhang,Yong-Fu WangAlpha Fodrin Ab IgG/IgA ELISA Kit (DEIA3120) - Creative

Anti-alpha Fodrin IgG/IgA is an indirect solid phase enzyme immunoassay (ELISA) for the quantitative measurement of IgG and IgA class autoantibodies against alpha-Fodrin in human serum or plasma.Cited by 29Publish Year 2004Author Amelia Ruffatti,Pierantonio Ostuni,Panagiotis Grypiotis,Costantino Botsios,Marta Tonello,ChiaraAnti-alpha-fodrin antibodies in patients with Sjögren's A recent meta-analysis encompassing 23 other studies concluded that the anti-AF antibody has moderate accuracy for the diagnosis of SS,with high specificity (83.1% in the IgG subtype and 82.8% in the IgA subtype) and relative low sensitivity (38% in the IgG subtype and 41.9% in the IgA subtype).These authors concluded that in order to avoid

Cited by 31Publish Year 2004Author Toshiaki Maruyama,Ichiro Saito,Yoshio Hayashi,Elizabeth Kompfner,Robert I.Fox,Dennis R.BurtonSensitivity and specificity for primary Sjögren's syndrome

Objective To investigate the sensitivity and specificity of anti-alpha-fodrin antibodies in patients with primary Sjögren's syndrome (pSS).Methods IgA and IgG anti-alpha-fodrin antibodies were measured in the sera of 80 patients with pSS,60 blood donors matched for age and sex,50 patients with systemic lupus erythematosus (SLE),30 with rheumatoid arthritis (RA),20 with systemic Clinical manifestations correlated to the prevalence of (iii) In addition to anti-Ro/La autoantibodies,anti -fodrin IgA and anti-MR3 autoantibodies seem to be promising diagnostic markers of SjS,but more studies are warranted to test their

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The NTG group showed higher serum anti-SSA and anti-SSB levels and lower anti--fodrin IgG/IgA levels than the HTG group.In the receiver operating characteristic curve analysis,the area under the curve (AUC) for serum MBP level was 0.917 in discriminating between controls andELISA Kitleri - BiocerProstaglandin F2 Alpha ELISA Kit.Proteinase 3 (PR3) ELISA Kit.Prouroguanylin Human ELISA.Progranulin ELISA.Proinsulin total (human) Prolactin (rat) ELISA.Protein A.Protein G ELISA.Prothrombin IgG,anti- ELISA.Prothrombin IgG/IgM,anti- ELISA.Prothrombin Screen,anti-PSA (Prostate Specific Antigen) PTH Intact (Parathyroid Hormone) PYY

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Goat Anti Human IgG IgA IgM UCB-Bioproducts

Description A sandwich ELISA for quantitative measurement of Goat Anti Alpha Fodrin IgG/IgA in samples from blood,plasma,serum,cell culture supernatant and other biological fluids.This is a high quality ELISA kit developped for optimal performance with samples from the particular species.Goat Anti Human IgG IgA IgM UCB-BioproductsThis anti-alpha-Fodrin IgG/IgA ELISA kit is validated to work with samples from whole blood,serum,plasma and cell culture supernatant.Description A quantitative ELISA kit for measuring Human in samples from biological fluids.

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Anti-alpha Fodrin IgG/IgA is an indirect solid phase enzyme immunoassay (ELISA) for the determination of IgG and IgA class autoantibodies against alpha-Fodrin in human serum or plasma.For research use only,not for use in diagnostic procedures.Radioimmunoassay (RIA) for the determination of human Thyroxine (T4) in serum.How to Equip Students to Be Mentally Tough PsychologyJan 17,2019·How to Equip Students to Be Mentally Tough Help prepare students for the path,not the path for students.Posted Jan 17,2019

Human Anti-alpha-Fodrin IgG/IgA ELISA kit (DEIA-BJ980

Human Anti-alpha-Fodrin IgG/IgA ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of the Anti-alpha-Fodrin IgG/IgA.This ELISA kit is for research use only,not for therapeutic or diagnostic applications.Human alpha-fodrin Antibody ELISA Kit (DEIA1222 Anti-idiotype Antibody Production . The Human alpha-fodrin Antibody ELISA kit is designed to detect and quantify the level of human alpha-fodrin Antibody in cell culture supernatant,serum,plasma and tissue. Alpha Fodrin Ab IgG/IgA ELISA Kit (DEIA3120) Customer Reviews.

Human alpha-fodrin Antibody ELISA Kit (DEIA1222

Anti-idiotype Antibody Production . The Human alpha-fodrin Antibody ELISA kit is designed to detect and quantify the level of human alpha-fodrin Antibody in cell culture supernatant,serum,plasma and tissue. Alpha Fodrin Ab IgG/IgA ELISA Kit (DEIA3120) Customer Reviews.Identification of tear lipocalin as a novel autoantigen Nov 01,2005·Sensitivity and specificity for primary Sjögren's syndrome of IgA and IgG anti-alpha-fodrin antibodies detected by ELISA J Rheumatol ,31 ( 2004 ) ,pp.504 -

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The ELISA (enzyme-linked immunosorbent assay) is a widely used application for detecting and quantifying proteins and antigens from various samples.Target-specific ELISA kits are available from a variety of manufacturers and can help streamline your immunodetection experiments.METHOD OF DIAGNOSING AND MONITORING THE6 out of the 99 patients (6.06%) showed an elevated IgG and/or IgA anti-alpha-fodrin level compared with 10 out of the 27 patients (37.04%) with acute relapses (P<0.001).The antibody level decreased in all patients after treatment with steroids.

METHOD OF DIAGNOSING AND MONITORING THE

6 out of the 99 patients (6.06%) showed an elevated IgG and/or IgA anti-alpha-fodrin level compared with 10 out of the 27 patients (37.04%) with acute relapses (P<0.001).The antibody level decreased in all patients after treatment with steroids.Method of diagnosing Sjogren's syndrome - Matthias,Torsten2.1 Distribution of IgA And IgG Antibodies Against -Fodrin In Patients' And Control Samples .In 160 sera from blood donors,the mean (± standard deviation) of the concentration of IgA and IgG antibodies against -fodrin was respectively 9.2 U/ml±5.5 U/ml and 11.1 U/ml±7.2 U/ml.

Molecular Analysis of the Human Autoantibody Response to

Jul 01,2004·A secondary Ab capable of detecting both IgG and IgA was used,because anti--fodrin Ab of both the IgG and IgA have been suggested to be elevated in SS sera.As shown in Figure 1,elevated -fodrin Ab levels were observed in both American and Japanese SS patients compared to the RA and SLE patient groups and healthy individuals.Molecular Analysis of the Human Autoantibody Response toTo investigate the specificity and sensitivity of anti--fodrin Abs for SS,serum from patients with SS,RA,SLE,and healthy individuals were tested for binding to mouse brain -fodrin by ELISA.A secondary Ab capable of detecting both IgG and IgA was used,because anti--fodrin Ab of both the IgG and IgA have been suggested to be elevated in SS sera.

Molecular analysis of the human autoantibody response to

Jul 01,2004·A secondary Ab capable of detecting both IgG and IgA was used,because anti--fodrin Ab of both the IgG and IgA have been suggested to be elevated in SS sera.As shown in Figure 1,elevated -fodrin Ab levels were observed in both American and Japanese SS patients compared to the RA and SLE patient groups and healthy individuals.Molecular analysis of the human autoantibody response to Jul 01,2004·A secondary Ab capable of detecting both IgG and IgA was used,because anti--fodrin Ab of both the IgG and IgA have been suggested to be elevated in SS sera.As shown in Figure 1,elevated -fodrin Ab levels were observed in both American and Japanese SS patients compared to the RA and SLE patient groups and healthy individuals.

Name and Intended Use Summary and Explanation of

Alpha Fodrin Ab IgG/IgA ELISA Kit ( Cat # KA1087 V.01 ) For research use only Name and Intended Use Anti-alpha Fodrin IgG/IgA is an indirect solid phase enzyme immunoassay (ELISA) for the quantitative measurement of IgG and IgA class autoantibodies against alpha-Fodrin in human serum or plasma.Summary and Explanation of the TestPrevalence of IgG AntiFodrin Antibodies in Sjögren's Concentrations of anti-alpha-fodrin antibodies (IgG and IgA) were also measured by ELISA with the purified protein (ORGENTEC Diagnostika GmbH,Mainz,Germany) [21].

SPTAN1 - Creative Diagnostics

Creative diagnostics provides SPTAN1 antibodies and elisa kits for science research use,feel free to contact us.USA / Tel 1-631-624-4882 Email Product Search Google Search Gene SearchSPTAN1 - Creative DiagnosticsCreative diagnostics provides SPTAN1 antibodies and elisa kits for science research use,feel free to contact us.USA / Tel 1-631-624-4882 Email Product Search Google Search Gene Search

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Unconjugated Whole IgG Rabbit anti-SPTAN1/Alpha II-spectrin Antibody,Affinity Purified suitable for WB,IHC,IHC-IF applications.Visit Bethyl for all your antibody needs.We support COVID-19 (SARS-CoV-2) research and are operating in accordance to CDC and government guidelines.SPTAN1/Alpha II-spectrin Antibody Bethyl Laboratories,Inc.Unconjugated Whole IgG Rabbit anti-SPTAN1/Alpha II-spectrin Antibody,Affinity Purified suitable for WB,IHC,IHC-IF applications.Visit Bethyl for all your antibody needs.We support COVID-19 (SARS-CoV-2) research and are operating in accordance to CDC and government guidelines.

Sensitivity and Specificity for Primary Sjögrens

sensitivity and specificity for pSS of the combined determination of IgA and IgG anti--fodrin anti-bodies were 40% and 58.18%,respectively.Conclusion.The prevalences of IgA and IgG anti--fodrin antibodies in our patients with pSS and other chronic autoimmune diseases have induced us to doubt their use as diagnostic markers of pSS.Sensitivity and specificity for primary Sjögren's syndrome OBJECTIVE To investigate the sensitivity and specificity of anti-alpha-fodrin antibodies in patients with primary Sjögren's syndrome (pSS).METHODS IgA and IgG anti-alpha-fodrin antibodies were measured in the sera of 80 patients with pSS,60 blood donors matched for age and sex,50 patients with systemic lupus erythematosus (SLE),30 with rheumatoid arthritis (RA),20 with systemic

Small Interfering RNA Targeting a-Fodrin Suppressing the

·Anti-a-fodrin IgG and IgA antibodies were critical to diagnosing pSS.[5] The results of this study underscored the complexity of the immune regulation mechanism by a-fodrin in the SS mice.Our ultimate goal was to understand the role of a-fodrin in regulating the levels of inflammatory factors in pathogeny of SS mice.Some results are removed in response to a notice of local law requirement.For more information,please see here.

Some results are removed in response to a notice of local law requirement.For more information,please see here.Previous123456NextSmall Interfering RNA Targeting -Fodrin Suppressing the

·Anti--fodrin IgG and IgA antibodies were critical to diagnosing pSS.The results of this study underscored the complexity of the immune regulation mechanism by -fodrin in the SS mice.Our ultimate goal was to understand the role of -fodrin in regulating the levels of inflammatory factors in pathogeny of SS mice.The Journal of Rheumatology Volume 32,no.1In 2003,we repeated the measurement of anti--fodrin in the sera of 46 patients with SS and healthy blood donors,using the American-European Consensus criteria4 for SS and using the same ELISA kit for detection of antibodies.The sensitivity for IgA and IgG anti--fodrin was 17.3% and 28.2%,the specificity 93.3% and 100%,respectively.

The Journal of Rheumatology Volume 32,no.1

blood donors.Autoantibodies against class IgA and IgG-type -fodrin were detected by the same commercial ELISAkit used by Ruffatti,et al.In the year 1998,European Community Study Group criteria2 were used to diagnose SS.The sensitivity for IgA and IgG anti--fodrin for SS was 37.3% and 38.8%,respectively.The specificity was 93.3% for both iso-The accuracy of the anti--fodrin antibody test for IgA and IgG anti-alpha-fodrin antibodies were measured in the sera of 80 patients with pSS,60 blood donors matched for age and sex,50 patients with systemic lupus erythematosus (SLE),30 with

The importance of alpha-fodrin antibodies in the diagnosis

Jul 01,2005·In RA+SS,anti-alpha-fodrin IgA was detected to be 10% and IgG was negative; however,anti-Ro antibodies and anti-La antibodies were found to be 40% and 20% respectively.In SLE+SS,anti-alpha-fodrin IgA was found to be 20% and IgG was found to be 10%,but anti-Ro and anti-La antibodies were found to be 90% and 20% respectively.Treatment of sicca symptoms with hydroxychloroquine in Eight patients were positive for -fodrin IgG that the presence of -fodrin antibodies might indicate an active and/or IgA at baseline.One patient was anti-Ro antibody glandular inflammation [6].negative and was diagnosed according to a positive histology,There is no established disease-modifying treatment of objective this patient was also

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