In 2012 a large outbreak of hand,foot,and mouth disease (HFMD) widely spread over China,causing more than 2 million cases and 567 deaths.Our purpose was to characterize the major pathogens responsible for the 2012 HFMD outbreak and analyze the4.9/5Price Range $1.25 - $1.50A case report of a teenager with severe hand,foot,and Feb 13,2019·In addition,ELISA for anti-EV71 IgM levels in CSF and blood samples are also used to confirm the viral infection [ 14,15 ].HFMD occurs mostly in children under the age of 5 years [ 4,16 ].However,adult cases of HFMD caused by CVA16 virus have
Hand-foot-mouth disease is caused by enteroviruses,in-cluding coxsackievirus A16 and enterovirus 71,and this disease is a benign,self-limited viral exanthem that most frequently affects children less than 10 years5.The charac-teristic papulovesicular eruptions involve the mouth and the palms and soles5.As a difference from the vesicles onA Guide to Clinical Management and Public Healthfor Hand,Foot and Mouth Disease (HFMD) Introduction H and,foot and mouth disease (HFMD) is a common infectious disease caused by a group of enteroviruses,including Coxsackievirus A16 (CA16) and Enterovirus 71 (EV71).Infection with EV71 is of particular concern as it can cause severe disease in children,sometimes resulting in death.
Enterovirus 71 (EV71) is the major causative pathogen of human hand,foot,and mouth disease (hHFMD) and has evolved to use various cellular receptors for infection.However,the relationship between receptor preference and EV71 virulence has not been fully revealed.By using reverse genetics,we identified that a single E98K mutation in VP1 is responsible for rapid viral replication in vitro.Abnormalities of ILC1 in children with hand,foot and Dec 01,2020·EV71 is considered one of the major pathogens leading to HFMD in children under 5 years old and is commonly diagnosed by PCR detection ( Kloverpris et al.,2016 ).EV71 infection is often predominantly attributed to severe HFMD accompanied by CNS complications ( Nasri et al.,2007 ).
in children with EV71 infection in HFMD,which is an important indicator to evaluate the progress of the disease.However,the gene polymorphism of b1 adrenergic receptor G1165C have no signicant correlation,not only with the susceptibility and severity of EV71 infection in hand,foot and mouth disease,but also with the levels of catecholamine.Author Qianwen Li,Yimeng Wang,Zhengying Bian,Yue Gao,Yu Zeng,Lei Tang,Tiejun Tang,Ye Tian,Wei GuoPublish Year 2020Hand-Foot-and-Mouth Disease Radiology KeySep 16,2016·And the diagnosis can be defined based on evidence from serological test and etiological examination.1.After the onset,EV71 nucleic acid is detected positive or EV71 virus is isolated from stool specimen or mouth-rinsed fluid.2.
Hand,foot,and mouth disease (HFMD) is caused mainly by enterovirus 71 (EV71) and other enteroviruses (EVs) such as Coxsackie A16 in China.EV71 infection can lead to severe clinical Bedside immunochromatographic test for enterovirus 71 Nov 01,2013·1.Background.Enterovirus 71 (EV71) causes epidemics annually in the Asia-Pacific area and occasional outbreaks in Europe or America,posing a major threat to child health .EV71-associated diseases include herpangina,handfootmouth disease (HFMD),meningitis and encephalitis with subsequent cardiopulmonary collapse or mortality.
Introduction Hand,foot,and mouth disease continues to cause seasonal epidemics in the Asia-Pacific Region.Since the current Enterovirus 71 vaccines do not provide cross-protection for all Enterovirus species that cause hand,foot,and mouth disease,there is an urgent need to identify appropriate detection tools and best practice to prevent its transmission and to effectively control its CD4 T-Cell-Independent Antibody Response Reduces EV71-specific IgM was also detected in sera of CD4 / mice with kinetics and titers comparable to those of wild-type mice from days 711 p.i.However,EV71-specific IgM was not detected in sera of B / mice from days 07 p.i.
This test is a single use,rapid device intended for qualitative detection of IgM-class antibodies to human Enterovirus 71 (EV71) in serum,plasma or whole blood samples.It is intended to be used in clinical laboratories for early diagnosis and management of patients related to infection with EV71.CDIA Human Enterovirus 71 IgM Test Kit - CreativeThis test is a single use,rapid device intended for qualitative detection of IgM-class antibodies to human Enterovirus 71 (EV71) in serum,plasma or whole blood samples.It is intended to be used in clinical laboratories for early diagnosis and management of patients related to infection with EV71.
Human Enterovirus 71(EV71-IgM) in human whole blood,serum or plasma.This test is a screening reagent.All positive sample must be confirmed by other methodologies.This test is intended for healthcare professional use only.PACKAGE SIZE 1 kit /box,10 kits /box,25 kits,/box,50 kits /box Summary EV71 is one of the main pathogens of hand,foot and mouth disease(HFMD),which canCited by 292Publish Year 2010Author S.S.Y.Wong,C.C.Y.Yip,S.K.P.Lau,K.Y.YuenHand Foot and Mouth Disease - ClinLab NavigatorViral culture is the gold standard for diagnosing HFMD,but the final results can take nearly a week.Newly developed IgM-capture enzyme-linked immunosorbent assays (ELISAs) for coxsackievirus A16 and enterovirus 71 are available.In the first week of disease,the IgM detection rate is 90.2% for enterovirus 71 and 68% for coxsackievirus A16.
Cited by 2Publish Year 2019Author Ying-Fu Chen,Lan Hu,Feng Xu,Cheng-jun Liu,Jing LiEV71 infection induces neurodegeneration via activating
Enterovirus 71 (EV71) is an RNA virus that causes hand-foot-mouth disease (HFMD),com- monly causing mild symptom in infants,but in some cases also leading to severe diseases such as aseptic meningitis (AM),brain stem encephalitis (BSE),acute flaccid paralysis (AFP),and even fatal encephalitis in neonates .Cited by 4Publish Year 2013Author Kuan-Ying Arthur Huang,Kuan-Ying Arthur Huang,Shuan Yang,Shuan Yang,Kuo-Chien Tsao,Kuo-Chien TsEnterovirus 71 infection in children with hand,foot,and Jun 03,2015·However,given the high sensitivity and convenience,finger tip blood EV71 IgM test can be used as a rapid point-of-care screen tool and an essential supplement for the early diagnosis of EV71 infection to help clinicians timely recognize severe EV71-associated diseases.
Cited by 60Publish Year 2015Author Ying Wang,Ying Wang,Gang Zou,Aimei Xia,Xiangshi Wang,Jiehao Cai,Qianqian Gao,Qianqian Gao,Sh(PDF) Evaluation of human enterovirus 71 and
Jan 11,2012·Hand-foot-and-mouth disease (HFMD) is caused mainly by the human enterovirus type 71 (HEV71) and the Coxsackievirus A group type 16 (CVA16).Large outbreaks ofCited by 60Publish Year 2015Author Ying Wang,Ying Wang,Gang Zou,Aimei Xia,Xiangshi Wang,Jiehao Cai,Qianqian Gao,Qianqian Gao,ShHuman enterovirus 71 and hand,foot and mouth disease Jan 08,2010·The genome of human enterovirus 71 (HEV-71) is about 74 kb in size,which is flanked by 5 and 3 untranslated regions.The protein-coding region can be divided into three regions P1 encodes for the structural proteins VP4,VP2,VP3,and VP1; P2 and P3 for the non-structural proteins 2A,2B,2C and 3A,3B,3C,3D,respectively [Reference Muir 9,Reference McMinn 10].
Cited by 60Publish Year 2015Author Ying Wang,Ying Wang,Gang Zou,Aimei Xia,Xiangshi Wang,Jiehao Cai,Qianqian Gao,Qianqian Gao,Shev71 igm rapid test kit,ev71 igm rapid test kit Suppliers
ev71 igm kit per il test rapido Intended Use IgM antibodies to EV 71 Rapid Test (Colloidal Gold) is based on the principle of colloidal gold enhanced,rapid immunocharomatographic assay for the determination of IgM antibodies to EV 71 in human whole blood/serum/plasma,as an aid in the clinical assessment of Enterovirus 71 infection.Cited by 65Publish Year 2010Author Feihai Xu,Qiang Yan,Hua Wang,Jianjun Niu,Liang Li,Fengcai Zhu,Shuizhen He,Shiyin Zhang,ZuxinEstimated Reading Time 9 minsProteomic analysis of extremely severe hand,foot and Aug 20,2013·EV71 virus can be detected by testing viral antigens,viral genomic RNA and antiviral antibodies in HFMD patients [13-15],however,no quick method has been established to distinguish mild HFMD from severe HFMD during the rapid progression of symptoms in fatal cases of EV71 infection.
Cited by 8Publish Year 2013Author Li Deng,Hong-Ling Jia,Chao-Wu Liu,Yu-Fen Xu,Li-Jia Mao,Chun-Hui He,Gen-Quan Yin,Jun-Hong Lin,Enterovirus 71 infection in children with hand,foot,and
The blood anti-EV71 IgM assay showed a sensitivity of 93.30 % and a specificity of 50 %.Conclusions EV71 C4a remained the predominant subgenotype circulating in Shanghai.The severity of the EV71 infection is not associated with the virulence determinants in VP1.Coxsackie a16 coxsackievirus a16 infection is very Hand-foot-and-mouth disease (HFMD) is a viral illness caused most commonly by coxsackievirus A16 (CVA16) and enterovirus 71 (EV71).The disease mainly affects pediatric populations younger than 5 years and is characterized by lesions of the oral mucosa,palms,and soles,lasting for 7 to 10 days
Therefore,detectable titers,especially those >1:32,should be considered diagnostic.Confirmed serodiagnosis is made by demonstration of a four-fold change in titers between.Hand-foot-and-mouth disease (HFMD) is a viral illness caused most commonlyDetection of serum immune factors in children with hand Sep 25,2017·Abstract.Objective To detect serum immune factors in children with hand-foot-and-mouth disease (HFMD),and to explore the clinical significance.Methods A total of 28 severe hand-foot-and-mouth disease (HFMD) patients with enterovirus 71 (EV71) infection,37 mild HFMD patients with EV71 infection,and 23 mild HFMD patients with coxsackievirus A16 (CVA16) infection were
of IgM and serum levels of TNF-,INF-,IL-8,IL-12 and IL-18 were also explored.Materials and Methods Patients Twenty-eight severe hand-foot-and-mouth disease (HFMD) patients with enterovirus 71 (EV71) infection,37 mild HFMD patients with EV71 infection,and 23 mild HFMD patients withDevelopment of a Dot-immunoenzyme Filtration AssayFIGURE 2 Dot-immunogold filtration assay for detection of enterovirus 71 (EV71).A nitrocellulose membrane was exposed first to human immunoglobulin (Ig)M (upper dot,control) or to EV71 VP1 protein (lower dot,test),then to serum samples from patients with hand,foot and mouth disease or healthy controls.IgM that remained
FIGURE 2 Dot-immunogold filtration assay for detection of enterovirus 71 (EV71).A nitrocellulose membrane was exposed first to human immunoglobulin (Ig)M (upper dot,control) or to EV71 VP1 protein (lower dot,test),then to serum samples from patients with hand,foot and mouth disease or healthy controls.IgM that remainedEV71 Rapid Test Kit - Creative DiagnosticsEV71.Rapid CDIA TM EV71 kits are intended for the detection of hand,foot,and mouth disease by detecting EV71 antibodies..EV71 infection is usually found among young children.It most commonly presents with symptoms of HFMD,characterized by fever,sores in the mouth,and a rash with blisters.
EV71.Rapid CDIA TM EV71 kits are intended for the detection of hand,foot,and mouth disease by detecting EV71 antibodies..EV71 infection is usually found among young children.It most commonly presents with symptoms of HFMD,characterized by fever,sores in the mouth,and a rash with blisters.EV71(HFMD) Test - ALUXBIOWas this helpful?Enterovirus 71 IgM Antibody POCT Test KitsEV-71 IgM DOT ELISA,EV-71 IgM ELISA and EV-71 IgM Dot Filtration Test Kits are used for the qualitative determination of IgM-class antibodies to human enterovirus-71 (EV71) in serum or plasma samples.These EV-71 Immunoassay kits are intended to be used in clinical laboratories for early diagnosis and management of patients infected with Enterovirus 71,a.k.a.the 'hand-foot-mouth
EV71(HFMD) Test Enterovirus 71 (EV71),one of the major causative agents for hand,foot and mouth disease (HFMD).One Step IgM antibodies to Enterovirus 71 Test is a rapid direct binding test for the qualitative detection of IgM antibodies to Enterovirus 71 in human serum/plasma/whole blood as an aid in the clinical assessment of Enterovirus 71 infection.Effective in vivo therapeutic IgG antibody against VP3 of
Apr 19,2017·Passive immunization is an effective option for treatment against hand,foot and mouth disease caused by EV71,especially with cross-neutralizing IgG monoclonal antibodies.In this study,an
This kit is used to qualitatively detect the EV71- IgM antibody in human blood,serum or plasma samples.It is a diagnosis reagent of EV early infection in clinical diagnosis.Enterovirus type 71 is one of the Picornaviridae virus (enterovirus,EV) genus,group A.It hasEnterovirus 71 Maternal Antibodies in Infants,Taiwan Dec 10,2010·Enterovirus 71 (EV71) was first isolated in California,USA,in 1969.Since then,EV71 has been isolated globally and causes life-threatening outbreaks in young children in Asia ( 4 10 ).National surveillance data and epidemiologic studies show that infants have an increased risk of severe EV71 infections in Taiwan ( 6 11 ).
Jun 03,2015·Blood EV71-IgM-Colloidal Gold immunochromatographic assay is easy to perform and provides the result within 15 min.It has high sensitivity and negative predict value but low specificity and positive predict value,therefore,EV71-IgM-Colloidal Gold assay as the confirmatory test for diagnosing EV71 infection was not recommended.Enterovirus 71 infection in children with hand,foot,and Keywords Enterovirus 71,Hand,foot and mouth disease,VP1 sequence,Neutralizing antibody,EV71 diagnosis Background Hand,foot,and mouth disease (HFMD) has been an emerging highly contagious disease in children in countries of the Western Pacific Region since the late nineties,posing a serious public health threat.HFMD is usually
Jan 20,2012·To characterize the human humoral immune response against enterovirus 71 (EV71) infection and map human epitopes on the viral capsid proteins.A series of 256 peptides spanning the capsid proteins (VP1,VP2,VP3) of BJ08 strain (genomic C4) were synthesized.An indirect enzyme-linked immunosorbent assay (ELISA) was carried out to detect anti-EV71 IgM and IgG in sera ofEpididymitis Caused by Coxsackievirus A6 in Association Coxsackievirus A6 (CV-A6) caused hand,foot,and mouth disease (HFMD) with a unique manifestation of epididymitis.The patient underwent operation due to suspicion of testicular torsion.Epididymitis was diagnosed by ultrasound examination.Enterovirus was detected from epididymal fluid by PCR and typed by partial sequencing of viral protein 1 as CV-A6.
Two colloidal gold immunochromatographic assays (CGIAs) for detection of EV71- and CA16- immunoglobulin M (IgM) were developed and evaluated.A total of 1465 sera collected from children with hand,foot,and mouth disease (HFMD),non-HFMD patients and healthy children.Estimated Reading Time 6 minsrapid test kit enterovirus 71,rapid test kit enterovirus The top countries of supplier is China,from which the percentage of rapid test kit enterovirus 71 supply is 85% respectively.Related Search wholesale igm ev71 test card enterovirus 71 ev71 igm antibody rapid test test igm torch igm 5 in 1 rapid test igm antibodies rapid test ev71 igm ev71 rapid test ev 71 rapid test ev71 igm rapid test rapid
EV71 IgM Rapid Test (colloid gold) is a single use,rapid device intended for qualitative detection of IgM-class antibodies to human enterovirus-71 (EV71) in serum,plasma or whole blood samples.It is intended to be used in clinical laboratories for early diagnosis andEvaluation of human enterovirus 71 and coxsackievirus A16 Jan 11,2012·Hand-foot-and-mouth disease (HFMD) is caused mainly by the human enterovirus type 71 (HEV71) and the Coxsackievirus A group type 16 (CVA16).Large outbreaks of disease have occurred frequently in the Asia-Pacific region.Reliable methods are needed for diagnosis of HFMD in childen.IgM-capture ELISA,with its notable advantages of convenience and low cost,provides a potentially
May 13,2021·Introduction.Hand,foot and mouth disease (HFMD) can jeopardize childrens health in the long term ().Enterovirus 71 (EV71) was the main pathogen of HFMD,at previous studies ().As EV71 vaccine has been extensively applied clinically,the infection rate of EV71 has decreased (),whereas the incidence of HFMD has been elevated over the past few years in some areas ().Frontiers A 10-Day-Old Murine Model of Coxsackievirus A6 May 13,2021·Introduction.Hand,foot and mouth disease (HFMD) can jeopardize childrens health in the long term ().Enterovirus 71 (EV71) was the main pathogen of HFMD,at previous studies ().As EV71 vaccine has been extensively applied clinically,the infection rate of EV71 has decreased (),whereas the incidence of HFMD has been elevated over the past few years in some areas ().
·Sunita S,Chow V T K,Phoon M C,et al.Direct Detection of Enterovirus 71 (EV71) in Clinical Specimens from a Hand,Foot,and Mouth Disease Outbreak in Singapore by Reverse Transcription-PCR with Universal Enterovirus and EV71-Specific Primers.Hand,foot,and mouth disease From self-limited to fatal Aug 27,2018·Serologic testing for A16 and enterovirus 71 (IgM) is available.Infected patients shed virus for 2-4 weeks and virus is stable in the environment resulting in fecal-oral or oral-oral transmission.
Apr 01,2014·Introduction.Hand,foot,and mouth disease is a common infectious disorder caused by various enteroviruses; enterovirus 71 (EV71) and Coxsackie virus A16 (CV-A16) are the most commonly reported.1 Children younger than 5 years are especially prone to hand,foot,and mouth disease,and most patients show self-limiting illness typically including fever,skin eruptions on hands and feet,and Hand-Foot-Mouth Disease Wholepower BiotechHand-Foot-Mouth Disease Hand-Foot-Mouth Disease.Packing Size 48 Tests Test Name.Pan Enterovirus RNA.Enterovirus 71 RNA.Coxsackievirus A16 RNA.EV71 CA 16 RNA.EV71,CA 16 Enterovirus RNA.Coxsackie Virus A6 RNA. COVID-19 IgG/IgM Antibody Tri-lines Rapid Diagnostic Tests.RT - PCR ASSAYS
EV71 IgM Rapid Detection Kit.The EV71 IgM Rapid Test Cassette is a sandwich lateral flow chromatographic immunoassay for the qualitative detection of IgM-class antibodies to human Enterovirus 71 (EV71) in human whole blood,serum or plasma.It is intended to be used as a screening test and as an aid in the diagnosis of infection with EV71.Immunologic Characterization of Cytokine Responses to INTRODUCTION.Hand,foot,and mouth disease (HFMD) is a commonly seen disease that inflicts children worldwide,characterized by mucocutaneous papulovesicular rashes on hands,feet,mouth,and buttocks lesions,and sometimes only with mouth disease (herpangina).1 The disease is generally mild and self-limited; however,in recent years,an increasing frequency of mortality associated with
Enterovirus 71 (EV71) is a major pathogen for severe hand,foot,and mouth disease (HFMD),which leads to severe neurological complications and has high morbidity and mortality.Reliable biomarker for the prediction of deterioration in EV71-infected children with central nervous system (CNS) involvement may reduce the cardiopulmonary failure and mortality.Isolation of subgenus B adenovirus during a fatal outbreak Sep 18,1999·In mid-1997,several children died in Sarawak,Malaysia,during an epidemic of enterovirus-71 (EV71) hand,foot,and mouth disease.The children who died had a febrile illness that rapidly progressed to cardiopulmonary failure and the cause was not satisfactorily resolved.
EV71 infection,fasting glucose,procalcitonin (PCT) and NT-proBNP levels were each associated with the severity of HFMD.Plasma NT-pro-BNP level appears to be a useful biological marker for predicting the severity and mortality of HFMD.Background Severe hand,foot and mouthOriginal Article Cellular immunity status and cytokine EV71 specific IgM was measured at onset of disease by the Diagnostic Kit for IgM Antibody to EV71 (ELISA) (Beier Bioengineering,Beijing,China).Sensitivity and specificity were 85.1% and 97.0%,respectively.EV71 isolate (GenBank accession number) was purified and inactivat-ed as an antigen for use in the stimulation of
Oct 15,2007·The primary manifestation of EV71 infection during periods of epidemicity is hand-foot-and-mouth disease .The largest reported outbreak of EV71 disease occurred in Taiwan (in 1998) and included 78 fatalities (34 were the result of laboratory-confirmed EV71 disease) [ 10 ].Performance of Detecting IgM Antibodies against Jun 30,2010·Enterovirus 71 (EV71) and coxsackievirus A16 (CA16) are the principal pathogens of hand foot and mouth disease (HFMD).EV71 is of special concern because it is more likely to induce severe complications and mortality than other enteroviruses,and has become endemic in Southeast Asia for tens of years,.
Enterovirus 71.Chinese surveillance data from 2008-2012 of more than 7 million children with hand-foot-and-mouth disease identified the highest incidence to be in children aged 12-23 months.Children younger than 6 months had the highest risk for severe and fatal disease,withPrevalence and Management of Severe Hand,Foot,and MouthJul 10,2020·Background.Hand,foot,and mouth disease (HFMD) is a contagious viral disease caused by more than 20 enteroviruses,including enterovirus 71 (EV71) and coxsackievirus A16 (CA16) (1,2).It usually affects infants and children younger than 5 years.
Aug 20,2013·To clarify the molecular mechanisms that participate in the severe hand,foot and mouth disease (HFMD) infected by Enterovirus 71 and to detect any related protein biomarkers,we performed proteomic analysis of protein extracts from 5 extremely severe HFMD children and 5 healthy children.The protein profiles of them were compared using two-dimensional electrophoresis.Proteomic analysis of extremely severe hand,foot and Aug 20,2013·To clarify the molecular mechanisms that participate in the severe hand,foot and mouth disease (HFMD) infected by Enterovirus 71 and to detect any related protein biomarkers,we performed proteomic analysis of protein extracts from 5 extremely severe HFMD children and 5 healthy children.The protein profiles of them were compared using two-dimensional electrophoresis.
·A Guide to Clinical Management and Public Health Response for Hand,Foot and Mouth Disease (HFMD); World Health Organization,2011.Downing C,Ramirez-Fort MK,Doan HQ,et al; Coxsackievirus A6 associated hand,foot and mouth disease in adults clinical presentation and review of the literature.J Clin Virol.2014 Aug60(4):381-6.doi 10.1016/j RESEARCH Open Access Enterovirus 71 viral capsidscreen IgM and IgG antibodies specifically for EV71 epi-topes.The EV71 sera were obtained from infected chil-dren at different stages of infectious disease (the acute or recovery stage).Convalescent sera from rabbits were immunized with inactivated BJ08 strain EV71 virus.Materials and methods Virus antigen and antigen peptides synthesis
EV71,the most recently recognized human en-terovirus in the family Picornaviridae,has been associated with outbreaks of hand-foot-and-mouth disease and central nervous system diseases (e.g.,aseptic meningitis,encephalitis,and poliomyelitis-like paralytic diseases) with persistent or transient paralysis (2,4,5).Despite some understanding Scavenger receptor class a,member 3 is associated with Hand,foot,and mouth disease (HFMD) spreads rapidly and has been recognized as a public health problem in recent years in China.Unfortunately,there is no effective vaccine or antiviral drug currently for EV71 infection.In this study,we aim to identify biomarker which are associated with for severity of EV71 infection cases using high-throughput RNA sequencing approach.
Jun 08,2008·Enterovirus 71 Infection Causative agent Enterovirus 71 (EV71) is a single stranded,RNA virus and one of the causative agents for hand,foot and mouth disease (HFMD).The disease occurs commonly in Southeast Asian areas,especially in summer and early autumn.Seroincidence Studies on Enterovirus 71 (EV71) and Jul 08,2018·EV71 IgM and CVA16 IgM rapid test kit were used to determine the presence of enterovirus 71 and coxasackie virus 16 respectively following the method of Zhang et al.,(2016).A positive test would have pathogen causing hand,foot and mouth disease outbreaks worldwide.ExpertReview of Anti-Infection Therapy.13,10611071.
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Many hospitals and some doctors offices can test ill patients to see if they have enterovirus infection.However,most cannot do specific testing to determine the type of enterovirus,like EV-A71.CDC and some state health departments can do this sort of testing by doing a specialized test called molecular sequencing on genetic material from
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Enterovirus 71; Hand-foot-and-mouth disease; Latex.agglutination test; Homogeneity; Ethyl-dimethyl-amino-propyl carbodiimide.Introduction.Hand,foot and mouth disease (HFMD) is a common childhood .disease that is characterized by fever,a rash on the hands and feet,and mouth ulcers [1,2].Most children,usually under five years old,with[A pathogen analysis within 174 cases of hand-foot-mouth Oct 01,2011·CA16 EV71 was 2.43 1.(2) There were 51 cases with CA16 IgM positive and 25 cases with EV71 IgM positive in the early collected sera,and in the later samples,98 cases with CA16 IgM positive and 32 cases with EV71 IgM positive.(3)The nucleotide homologies were 88.7%-98.5% of VP1 gene among CA16.
Apr 01,2010·OBJECTIVE To analyze the Enterovirus 71 infectious status about probably cases of hand-foot-mouse disease (HFMD).METHODS Collect the blood samples of HFDM children probably cases and test the IgG,IgM antibody by ELISA,analyzed the age and gender distribution.